Description

Miconazole Nitrate CAS NO 22832-87-7 is a synthetic antifungal agent belonging to the imidazole class, widely recognized for its potent activity against a broad spectrum of pathogenic fungi and yeasts. Its primary value lies in its efficacy as a key active pharmaceutical ingredient (API) for topical and systemic antifungal formulations. This compound is essential for manufacturers in the pharmaceutical and personal care industries developing products to treat fungal infections.

Application

• Pharmaceutical API: Primary active ingredient in topical creams, ointments, powders, and sprays for treating athlete's foot, ringworm, jock itch, and cutaneous candidiasis.
• Veterinary Medicine: Used in antifungal preparations for treating dermatological conditions in companion animals and livestock.
• Personal Care Products: Incorporated into medicated soaps, shampoos, and powders for antifungal and anti-dandruff properties.
• Oral & Vaginal Formulations: Used in the production of lozenges for oral thrush and suppositories/creams for vaginal yeast infections.
• Industrial Preservation: Potential application as a fungistatic agent in specific material preservation scenarios where microbial growth is a concern.

Basic Information

Product Name	Miconazole Nitrate
CAS No.	22832-87-7
Molecular Formula	C18H14Cl4N2O • HNO3
Molecular Weight	479.15 g/mol
Synonyms	Miconazole Nitrate; 1-[2-(2,4-Dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]-1H-imidazole nitrate; Micatin (trade name); Monistat (trade name); Daktarin (trade name); R 14889 (code number); (+/-)-Miconazole nitrate
EINECS	245-276-3

Quality Control

Our Miconazole Nitrate is manufactured under strict quality management systems. It is tested to meet relevant pharmacopeial standards such as USP, EP, and BP, ensuring high purity and consistent performance for pharmaceutical applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each batch to guarantee supply reliability and regulatory compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and away from moisture and direct light exposure to maintain stability and potency.

Specification

Item	Specification
Appearance	White or almost white, crystalline powder
Identification (IR)	Conforms
Identification (HPLC)	Conforms
Assay (HPLC)	98.5% - 101.0% (on dried basis)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity: ≤ 0.5% Total impurities: ≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.