Description

Miconazole is a potent synthetic imidazole antifungal agent widely recognized for its broad-spectrum activity against pathogenic fungi and yeasts. Its primary commercial value lies in its efficacy as a key active pharmaceutical ingredient (API) for the formulation of topical and systemic antifungal medications. This compound is essential for manufacturers in the pharmaceutical, personal care, and veterinary industries producing treatments for dermatological, mucosal, and systemic fungal infections.

Application

• Pharmaceutical API: Core ingredient in topical creams, ointments, powders, and sprays for athlete's foot, ringworm, jock itch, and cutaneous candidiasis.
• Oral & Vaginal Formulations: Used in lozenges for oral thrush and in suppositories/creams for vulvovaginal candidiasis.
• Veterinary Medicine: Incorporated into topical preparations for treating fungal infections in companion animals and livestock.
• Personal Care Products: Active agent in medicated powders, antifungal soaps, and specialized foot care products.
• Combination Therapies: Used in conjunction with corticosteroids (e.g., hydrocortisone) in anti-itch and anti-inflammatory creams.
• Industrial Preservation: Potential application as a fungistatic agent in specific material preservation contexts, subject to regulatory approval.

Basic Information

Product Name	Miconazole
CAS No.	22916-47-8
Molecular Formula	C18H14Cl4N2O
Molecular Weight	416.13 g/mol
Synonyms	1-[2-(2,4-Dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]-1H-imidazole; Micatin; Monistat; Daktarin; Gyno-Daktarin; Albistat; Miconazole Nitrate (salt form); R 14889
EINECS	245-324-7

Quality Control

Our Miconazole is manufactured under strict quality management systems, targeting compliance with major pharmacopoeial standards including USP, EP, and BP. Each batch undergoes comprehensive analytical testing for identity, potency, and purity. A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring full traceability and meeting the stringent requirements of pharmaceutical API procurement.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White or almost white crystalline powder
Identification (IR)	Conforms
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%
Microbial Enumeration	Meets EP/USP criteria

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.