Description

Isoconazole Nitrate is a synthetic imidazole derivative with potent antifungal activity. This compound is a critical active pharmaceutical ingredient (API) valued for its broad-spectrum efficacy against dermatophytes, yeasts, and molds. It is primarily required by the pharmaceutical industry for the formulation of topical antifungal creams, ointments, and powders to treat various skin infections.

Application

• Pharmaceutical API: Primary active ingredient in topical antifungal medications for human use.
• Dermatological Preparations: Formulated into creams, ointments, and lotions for treating athlete's foot, ringworm, and other cutaneous mycoses.
• Veterinary Medicine: Used in topical antifungal treatments for companion animals and livestock.
• Research & Development: Serves as a reference standard and building block in antifungal drug discovery and pharmacological studies.
• Cosmeceutical Products: Incorporated into specialized foot care powders and sprays for antifungal protection.

Basic Information

Product Name	Isoconazole Nitrate
CAS No.	24168-96-5
Molecular Formula	C18H14Cl4N2O·HNO3
Molecular Weight	479.14 g/mol
Synonyms	1-[2-(2,4-Dichlorophenyl)-2-[(2,6-dichlorophenyl)methoxy]ethyl]-1H-imidazole nitrate; Isoconazole mononitrate; Travogen; Fazol; Gyno-Travogen; Azet; (RS)-1-[2,4-Dichloro-β-[(2,6-dichlorobenzyl)oxy]phenethyl]imidazole nitrate
EINECS	Contact for details

Quality Control

Our Isoconazole Nitrate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity standards suitable for pharmaceutical applications. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee supply reliability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to almost white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any individual impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.