Description

(3-Bromo-4-Hydroxyphenyl)(Isoindolin-2-Yl)Methanone is a high-purity, advanced pharmaceutical intermediate characterized by its distinct brominated hydroxyphenyl and isoindolinone structure. This compound matters as a critical building block in modern medicinal chemistry, enabling the synthesis of novel active pharmaceutical ingredients (APIs) with targeted therapeutic effects. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of new drug candidates, particularly within oncology and central nervous system (CNS) therapeutic areas.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of complex drug molecules and novel active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies for new drug discovery programs.
• Organic Synthesis Building Block: Utilized in multi-step synthetic routes to construct complex heterocyclic frameworks.
• Chemical Biology Probes: Acts as a scaffold for developing molecular probes to study biological pathways and protein interactions.
• Contract Manufacturing (CMO): Supplied to contract research and manufacturing organizations (CROs/CMOs) for custom synthesis projects.
• Academic Research: Employed in university and institutional labs for methodological development and novel reaction studies.

Basic Information

Product Name	(3-Bromo-4-Hydroxyphenyl)(Isoindolin-2-Yl)Methanone
CAS No.	914298-65-0
Molecular Formula	C15H10BrNO2
Molecular Weight	316.15 g/mol
Synonyms	2-(3-Bromo-4-hydroxybenzoyl)isoindoline; 1-(3-Bromo-4-hydroxyphenyl)-2,3-dihydro-1H-isoindol-2-one; (3-Bromo-4-hydroxyphenyl)(2,3-dihydro-1H-isoindol-2-yl)methanone; 914298-65-0; Methanone, (3-bromo-4-hydroxyphenyl)-2,3-dihydro-1H-isoindol-2-yl-; BRD-K94211630
EINECS	Contact for details

Quality Control

Our (3-Bromo-4-Hydroxyphenyl)(Isoindolin-2-Yl)Methanone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.