Description

5'-Fluoro-2'-Iodoacetophenone is a high-purity, halogenated acetophenone derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both fluorine and iodine substituents, makes it a versatile intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries, particularly for developing active pharmaceutical ingredients (APIs) and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially in medicinal chemistry programs targeting CNS disorders and oncology.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, leveraging the fluorine atom for enhanced biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands and organocatalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as OLED (Organic Light-Emitting Diode) components and liquid crystals.
• Chemical Biology Probes: Utilized to develop molecular probes and tags for studying biological processes and protein interactions.
• Custom Synthesis and R&D: A valuable reagent for contract research organizations (CROs) and academic laboratories engaged in exploratory organic synthesis.

Basic Information

Product Name	5'-Fluoro-2'-Iodoacetophenone
CAS No.	914225-70-0
Molecular Formula	C8H6FIO
Molecular Weight	264.04 g/mol
Synonyms	1-(2-Fluoro-5-iodophenyl)ethanone; 2'-Fluoro-5'-Iodoacetophenone; 2-Fluoro-5-iodoacetophenone; 5-Iodo-2-fluoroacetophenone; 1-Acetyl-2-fluoro-5-iodobenzene; α-Fluoro-α'-iodoacetophenone; (2-Fluoro-5-iodophenyl)methyl ketone
EINECS	Contact for details

Quality Control

Our 5'-Fluoro-2'-Iodoacetophenone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity verification and NMR for structural confirmation, to ensure compliance with exacting standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency for your critical R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and storage should minimize exposure to direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.