Description

(4,5-Difluoro-2-Nitro-Phenyl)-Methanol is a high-value, multi-functional aromatic building block characterized by its difluoro and nitro substituents. This compound is essential for the synthesis of complex molecules, particularly in advanced pharmaceutical and agrochemical research where its unique substitution pattern enables precise structural modifications. It is primarily sought after by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and material science industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those containing fluorinated aromatic systems for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the difluoro and nitro groups contribute to biological activity and selectivity.
• Liquid Crystal & OLED Material Research: Serves as a building block for fluorinated organic electronic materials, contributing to improved performance in display and lighting technologies.
• Dye & Pigment Intermediate: Employed in the production of specialized dyes and pigments, where the nitro group is a key chromophore and the fluorine atoms fine-tune color properties.
• Cross-Coupling Reactions: The benzylic alcohol and halogenated aromatic ring make it a versatile substrate for Suzuki, Sonogashira, and other palladium-catalyzed cross-coupling reactions.
• Polymer Modification: Used to introduce fluorinated aromatic units into polymer backbones, altering physical properties like chemical resistance, thermal stability, and surface energy.

Basic Information

Product Name	(4,5-Difluoro-2-Nitro-Phenyl)-Methanol
CAS No.	914095-13-9
Molecular Formula	C7H5F2NO3
Molecular Weight	189.12 g/mol
Synonyms	2-Nitro-4,5-difluorobenzyl alcohol; (4,5-Difluoro-2-nitrophenyl)methanol; 4,5-Difluoro-2-nitrobenzenemethanol; 1-(Hydroxymethyl)-4,5-difluoro-2-nitrobenzene; 2-Nitro-4,5-difluorobenzylalcohol; Benzenemethanol, 4,5-difluoro-2-nitro-; 4,5-Difluoro-2-nitrobenzyl alcohol
EINECS	Contact for details

Quality Control

Our (4,5-Difluoro-2-Nitro-Phenyl)-Methanol is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistent batch-to-batch performance. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended storage temperature is 2-8°C for long-term stability. Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.