Description

n-[2-(1-Bromoethyl)Phenyl]-2,2,2-Trifluoroacetimidoyl Chloride CAS NO 913962-14-8 is a specialized organohalogen and organofluorine compound that serves as a high-value synthetic intermediate. Its molecular architecture, featuring both bromoethyl and trifluoroacetimidoyl chloride functional groups, makes it a critical building block for constructing complex molecules in advanced chemical synthesis. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those requiring the introduction of fluorine atoms or complex aromatic systems for enhanced bioactivity and metabolic stability.
• Agrochemical Synthesis: Used in the research and development of next-generation pesticides and herbicides, where the trifluoromethyl group can improve compound efficacy and environmental profile.
• Material Science Research: Serves as a monomer or functionalization agent in the development of specialty polymers and advanced organic materials with unique electronic or surface properties.
• Cross-Coupling Reactions: The bromoethyl moiety acts as a handle for versatile palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) to create complex biaryl structures.
• Ligand and Catalyst Development: Employed in the design and synthesis of novel ligands and organocatalysts for asymmetric synthesis and other catalytic processes.
• Fluorine Chemistry Studies: A valuable reagent for academic and industrial research focused on incorporating trifluoromethyl groups into organic molecules.

Basic Information

Product Name	n-[2-(1-Bromoethyl)Phenyl]-2,2,2-Trifluoroacetimidoyl Chloride
CAS No.	913962-14-8
Molecular Formula	C10H8BrClF3NO
Molecular Weight	330.53 g/mol
Synonyms	2,2,2-Trifluoro-N-[2-(1-bromoethyl)phenyl]acetimidoyl chloride; 1-Bromo-1-(2-{[(trifluoroacetyl)imino]methyl}phenyl)ethane; N-[2-(1-Bromoethyl)phenyl]-2,2,2-trifluoroethanimidoyl chloride; 913962-14-8; 2-(1-Bromoethyl)-N-(trifluoroacetyl)benzenecarboximidoyl chloride; Trifluoroacetic acid [2-(1-bromoethyl)phenyl]imino chloride
EINECS	Contact for details

Quality Control

Every batch of n-[2-(1-Bromoethyl)Phenyl]-2,2,2-Trifluoroacetimidoyl Chloride is manufactured and tested under strict quality management protocols to ensure consistency and reliability for your critical research and development processes. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as purity, identity, and impurity profiles. Our commitment to quality supports compliance with the stringent requirements of cGMP (current Good Manufacturing Practice) for pharmaceutical intermediates and other regulated applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5% w/w
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.