Description

(1S)-1-(2-Chloro-4-Fluorophenyl)Ethanol CAS NO 911218-03-6 is a high-purity chiral intermediate of significant importance in modern synthetic chemistry. Its value lies in its defined stereochemistry, which is critical for producing active pharmaceutical ingredients (APIs) with specific and desired biological activity. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical and agrochemical industries for the development and production of enantiomerically pure substances.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of novel, enantiomerically pure drug candidates, particularly in central nervous system (CNS) and anti-infective therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced, stereoselective pesticides and herbicides where the specific spatial orientation of the molecule affects efficacy.
• Asymmetric Catalysis Research: Serves as a valuable ligand precursor or chiral pool starting material in academic and industrial research focused on developing new catalytic methodologies.
• Fine Chemical Production: Employed in the manufacture of other specialty chemicals and advanced materials that require a high degree of stereochemical control.

Basic Information

Product Name	(1S)-1-(2-Chloro-4-Fluorophenyl)Ethanol
CAS No.	911218-03-6
Molecular Formula	C8H8ClFO
Molecular Weight	174.60 g/mol
Synonyms	(S)-1-(2-Chloro-4-fluorophenyl)ethanol; (1S)-1-(2-Chloro-4-fluorophenyl)ethan-1-ol; (-)-1-(2-Chloro-4-fluorophenyl)ethanol; (S)-(-)-1-(2-Chloro-4-fluorophenyl)ethanol; 2-Chloro-4-fluoro-α-methylbenzyl alcohol (S-form); α-Methyl-2-chloro-4-fluorobenzyl alcohol (S-); (S)-1-(2-Chloro-4-fluorophenyl)ethyl alcohol
EINECS	Contact for details

Quality Control

Our production of (1S)-1-(2-Chloro-4-Fluorophenyl)Ethanol adheres to stringent quality management systems, ensuring batch-to-batch consistency and high chemical purity. Quality is verified through comprehensive analytical techniques including chiral HPLC, NMR, and GC-MS. A Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles is provided with every shipment to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.