Description

Adapalene (Sodium Salt) is a high-purity pharmaceutical-grade active pharmaceutical ingredient (API) and a key synthetic retinoid derivative. This compound is essential for the formulation of advanced topical dermatological treatments, offering targeted therapeutic action. It is primarily required by pharmaceutical manufacturers and R&D laboratories specializing in dermatology and acne therapeutics.

Application

• Active Pharmaceutical Ingredient (API) in topical acne medications (e.g., creams, gels).
• Key Intermediate for the synthesis of novel retinoid-based compounds in pharmaceutical research.
• Reference Standard for quality control and analytical method development in QC/QA laboratories.
• Dermatological R&D for studying mechanisms of action against comedones and inflammation.
• Formulation Development for stability testing and compatibility studies in final drug products.

Basic Information

Product Name	Adapalene (Sodium Salt)
CAS No.	911110-93-5
Molecular Formula	C28H27NaO4
Molecular Weight	450.50 g/mol
Synonyms	Adapalene Sodium; Sodium Adapalene; 6-[3-(1-Adamantyl)-4-methoxyphenyl]-2-naphthoic Acid Sodium Salt; CD 271 Sodium Salt; Differin (Sodium Salt); Adapalenum Natricum; Adapalene Na; Adapalene Sodium Salt
EINECS	Contact for details

Quality Control

Our Adapalene (Sodium Salt) is manufactured under strict quality systems. It undergoes rigorous analytical testing to ensure it meets high-purity standards suitable for pharmaceutical applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each batch to support regulatory compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 5.0%
Related Substances (HPLC)	Individual impurity: ≤ 0.5% Total impurities: ≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.