Description

2,2,2-Trifluoro-1-(2,4-Difluoro-Phenyl)Ethanol is a high-value fluorinated aromatic alcohol building block. This compound is critical for the synthesis of advanced pharmaceutical intermediates and agrochemicals, where its unique trifluoromethyl and difluorophenyl groups impart desirable metabolic stability and lipophilicity. It is primarily sought by R&D chemists and process development teams in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: Key synthon for the development of active pharmaceutical ingredients (APIs), particularly in antifungal and central nervous system (CNS) drug candidates.
• Agrochemical Synthesis: Building block for novel herbicides, fungicides, and insecticides, leveraging fluorine's ability to enhance biological activity and environmental persistence.
• Liquid Crystal Materials: Used in the research and production of fluorinated liquid crystals for advanced display technologies.
• Organic Synthesis Reagent: Serves as a versatile fluorinated precursor in cross-coupling reactions, nucleophilic substitutions, and chiral synthesis.
• Polymer Modification: Imparts hydrophobic and oleophobic properties to specialty polymers and coatings.
• Chemical Research: Valuable reference standard and starting material in academic and industrial R&D for exploring new fluorination methodologies.

Basic Information

Item	Details
Product Name	2,2,2-Trifluoro-1-(2,4-Difluoro-Phenyl)Ethanol
CAS No.	910866-32-9
Molecular Formula	C8H5F5O
Molecular Weight	212.12 g/mol
Synonyms	2,2,2-Trifluoro-1-(2,4-difluorophenyl)ethanol; 1-(2,4-Difluorophenyl)-2,2,2-trifluoroethanol; α,α,α-Trifluoro-2,4-difluorobenzeneethanol; 2,4-Difluoro-α-(trifluoromethyl)benzyl alcohol; (2,4-Difluorophenyl)(trifluoromethyl)methanol; 910866-32-9; F3C-C(OH)(C6H3F2)H
EINECS	Contact for details

Quality Control

Our 2,2,2-Trifluoro-1-(2,4-Difluoro-Phenyl)Ethanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with complete traceability are provided with every shipment. We support custom synthesis and can tailor specifications to meet specific project requirements, including compliance with ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under a dry inert atmosphere (e.g., nitrogen or argon) for prolonged operations to prevent degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Related Substances (HPLC)	Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.