Description

Ethanone, 2-Iodo-1-(2,4,5-Trimethoxyphenyl)- is a specialized iodinated aromatic ketone derivative, serving as a valuable high-purity synthetic intermediate for advanced chemical synthesis. Its unique structure, featuring an electron-rich trimethoxyphenyl group and a reactive iodoacetyl moiety, makes it a critical building block for constructing complex molecules in pharmaceutical and agrochemical research. This compound is primarily sought by R&D chemists and process development scientists in the fine chemical and life sciences industries.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders or with complex heterocyclic architectures.
• Agrochemical Research: Used in developing new herbicides, fungicides, or plant growth regulators where the trimethoxy and iodo functional groups contribute to biological activity.
• Material Science Chemistry: Serves as a monomer or cross-linking agent in the development of advanced polymers, liquid crystals, or organic electronic materials.
• Chemical Biology & Proteomics: Potential use as a reactive handle for bioconjugation or as a scaffold in probe development due to the iodoacetone group's affinity for thiols.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies in cross-coupling reactions (e.g., Suzuki, Heck) and other transition metal-catalyzed transformations.
• Dye & Pigment Synthesis: Intermediate for creating specialized iodinated aromatic dyes and pigments with specific light-absorption properties.

Basic Information

Product Name	Ethanone, 2-Iodo-1-(2,4,5-Trimethoxyphenyl)-
CAS No.	909400-85-7
Molecular Formula	C11H13IO4
Molecular Weight	336.12 g/mol
Synonyms	2-Iodo-1-(2,4,5-trimethoxyphenyl)ethanone; 2',4',5'-Trimethoxy-2-iodoacetophenone; 1-(2,4,5-Trimethoxyphenyl)-2-iodoethanone; 2-Iodo-2',4',5'-trimethoxyacetophenone; α-Iodo-2,4,5-trimethoxyacetophenone; Iodinated Trimethoxyacetophenone; CAS 909400-85-7
EINECS	Contact for details

Quality Control

Our Ethanone, 2-Iodo-1-(2,4,5-Trimethoxyphenyl)- is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, essential for sensitive synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality system is designed to meet the stringent requirements of research and development as well as cGMP for early-phase pharmaceutical manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound is light-sensitive; prolonged exposure to light should be avoided to prevent decomposition. Keep the container tightly sealed when not in use to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.