Description

5-Octa-1,7-Diynyl-2'-Deoxyuridine is a chemically modified nucleoside analog, a key building block in advanced organic synthesis and medicinal chemistry research. Its unique structure, featuring an extended diynyl side chain, makes it a valuable precursor for developing novel probes, diagnostics, and therapeutic agents. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and life sciences sectors focused on nucleoside-based drug discovery and oligonucleotide synthesis.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel nucleoside-based antiviral and anticancer drug candidates.
• Bioconjugation & Probe Development: Utilized for creating labeled nucleosides and oligonucleotides for diagnostic assays and imaging studies due to its reactive alkyne groups.
• Medicinal Chemistry Research: Serves as a scaffold for structure-activity relationship (SAR) studies to optimize pharmacokinetic properties and biological activity.
• Oligonucleotide Synthesis: Used in the preparation of modified DNA strands for applications in antisense therapy, gene silencing, and molecular biology tools.
• Chemical Biology Tool: Enables click chemistry applications for tagging and pull-down experiments to study biomolecular interactions.
• Academic & Contract Research: A key reagent for universities and CROs engaged in cutting-edge synthetic and bioorganic chemistry projects.

Basic Information

Item	Details
Product Name	5-Octa-1,7-Diynyl-2'-Deoxyuridine
CAS No.	909398-18-1
Molecular Formula	C17H20N2O5
Molecular Weight	332.35 g/mol
Synonyms	5-(Octa-1,7-diyn-1-yl)-2'-deoxyuridine; 5-Octadiynyl-2'-deoxyuridine; 2'-Deoxy-5-(octa-1,7-diyn-1-yl)uridine; 5-(1,7-Octadiynyl)-2'-deoxyuridine; Modified 2'-Deoxyuridine; Nucleoside analog with diyne chain
EINECS	Contact for details

Quality Control

Every batch of 5-Octa-1,7-Diynyl-2'-Deoxyuridine is manufactured under strict quality management systems. We guarantee high purity and consistency through comprehensive analytical testing, including HPLC, NMR, and mass spectrometry. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to ensure it meets the stringent requirements of research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.