Description

7-Deaza-2'-Deoxy-7-Iodoadenosine is a modified nucleoside analog, specifically engineered for advanced biochemical and pharmaceutical research. This compound is a critical building block in the synthesis of oligonucleotides, enabling the study of nucleic acid structure, function, and therapeutic applications. It is primarily utilized by research institutions, diagnostic developers, and pharmaceutical companies engaged in antisense technology, probe development, and medicinal chemistry.

Application

• Antisense Oligonucleotide Synthesis: A key monomer for creating modified oligonucleotides used in gene silencing and therapeutic research.
• Diagnostic Probe Development: Used in the design of high-specificity probes for fluorescence in situ hybridization (FISH) and other molecular diagnostic assays.
• Medicinal Chemistry & Drug Discovery: Serves as a precursor in the development of nucleoside-based antiviral and anticancer agents.
• Biochemical Research: Employed in studies investigating DNA/RNA structure, enzyme mechanisms, and nucleic acid-protein interactions.
• Photocrosslinking Studies: The iodine atom can facilitate crosslinking experiments to study biomolecular interactions.

Basic Information

Product Name	7-Deaza-2'-Deoxy-7-Iodoadenosine
CAS No.	908130-61-0
Molecular Formula	C11H13IN4O3
Molecular Weight	376.15 g/mol
Synonyms	7-Iodo-7-deaza-2'-deoxyadenosine; 7-Deaza-7-iodo-2'-deoxyadenosine; 7-Iodo-tubercidin 2'-deoxyriboside; 2'-Deoxy-7-iodotubercidin; 7-Iodo-2'-deoxy-7-deazaadenosine; 7-Iodo-7-deaza-dA; 7-I-7-deaza-dA
EINECS	Contact for details

Quality Control

Our 7-Deaza-2'-Deoxy-7-Iodoadenosine is manufactured under strict quality systems to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry guidelines to support our customers' compliance needs in pharmaceutical development and diagnostic manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.