Description

2'-Deoxy-2'-Fluoro--D-Arabino-6-Azidouridine is a chemically modified nucleoside analog, a key building block in advanced pharmaceutical and biochemical research. This compound is valued for its unique structure, which incorporates both fluorine and azide functional groups, enabling its use in the synthesis of novel therapeutic agents and as a versatile probe in chemical biology. It is primarily required by research institutions and pharmaceutical companies engaged in the development of antiviral drugs, oligonucleotide therapeutics, and click chemistry applications.

Application

• Antiviral Drug Development: A critical intermediate in the research and synthesis of nucleoside-based antiviral agents targeting RNA viruses.
• Oligonucleotide Synthesis: Used in the preparation of modified oligonucleotides for antisense, siRNA, and mRNA technology platforms.
• Click Chemistry Reagent: The azide group facilitates bioorthogonal conjugation reactions (e.g., CuAAC) for labeling and bioconjugation studies.
• Chemical Biology Probe: Serves as a tool compound for studying enzyme mechanisms, such as those of polymerases and nucleoside kinases.
• Preclinical Research: Employed in the discovery and optimization stages of novel therapeutic candidates.
• Academic Research: Used in university and institutional labs for fundamental studies in medicinal chemistry and nucleic acid chemistry.

Basic Information

Product Name	2'-Deoxy-2'-Fluoro--D-Arabino-6-Azidouridine
CAS No.	908129-24-8
Molecular Formula	C9H10FN5O5
Molecular Weight	287.21 g/mol
Synonyms	6-Azido-2'-deoxy-2'-fluoroarabinouridine; 2'-F-6-N3-araU; 2'-Deoxy-2'-fluoro-6-azidouridine; 6-Azido-1-((2R,3S,5R)-3-fluoro-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione; 2'-F-ara-6-azido-U; 6-Azido-2'-fluoro-2'-deoxyarabinouridine; 2'-Fluoro-6-azido-2'-deoxyarabinouridine; 6-N3-2'-F-araU
EINECS	Contact for details

Quality Control

Our 2'-Deoxy-2'-Fluoro--D-Arabino-6-Azidouridine is manufactured under strict quality systems to ensure high purity and batch-to-batch consistency, suitable for research and development applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to industry best practices, and specifications can be aligned with customer requirements for advanced pharmaceutical research.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Assay (HPLC)	≥ 95.0%
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.