Description

3-Fluoroisonicotinoyl Chloride is a high-purity, reactive chemical intermediate essential for advanced organic synthesis. Its core value lies in its role as a versatile building block for introducing the 3-fluoroisonicotinate moiety into complex molecular architectures. This compound is critically needed by pharmaceutical and agrochemical R&D teams for the development of novel active ingredients, particularly in medicinal chemistry for creating targeted drug candidates.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs) and drug candidates, particularly in kinase inhibitor research.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides requiring specific fluorinated heterocyclic structures.
• Ligand and Material Science: Precursor for creating specialized ligands for catalysis and functional monomers for advanced polymeric materials.
• Chemical Research & Development: Essential reagent in academic and industrial labs for exploring new fluorinated heterocyclic compounds and their properties.
• Peptide Modification: Employed to introduce fluorinated nicotinic acid derivatives into peptides to alter their biological activity and stability.

Basic Information

Product Name	3-Fluoroisonicotinoyl Chloride
CAS No.	903592-75-6
Molecular Formula	C6H3ClFNO
Molecular Weight	159.55 g/mol
Synonyms	3-Fluoropyridine-4-carbonyl chloride; 3-Fluoro-4-pyridinecarbonyl chloride; 3-Fluoropyridine-4-carboxylic acid chloride; 3-Fluoropyridine-4-carbonyl chloride; 4-Pyridinecarbonyl chloride, 3-fluoro-; 3-Fluoroisonicotinic acid chloride; 3-Fluoro-4-pyridylcarbonyl chloride; 3-Fluoropyridine-4-carboxylic chloride
EINECS	Contact for details

Quality Control

Our 3-Fluoroisonicotinoyl Chloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and FTIR, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment supports applications requiring traceability and consistency, from early-stage research to scale-up development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from strong bases, oxidizing agents, and sources of moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.