Description

1Alpha-Deoxy-1Alpha-Azido-4Alpha-Deoxy-4Alpha-(Thymin-1-Yl)-2,3Alpha:2Alpha,5Alpha-Dianhydro-L-Altritol is a sophisticated nucleoside analogue derivative, a key synthetic intermediate in advanced pharmaceutical research. Its complex structure, featuring azido and thyminyl moieties, makes it a valuable building block for the development of novel antiviral and anticancer agents. This high-purity compound is essential for research and development chemists in the pharmaceutical and biotechnology sectors, particularly those focused on nucleoside-based therapeutics and prodrug design.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel nucleoside analogue drugs targeting viral infections and cancer.
• Antiviral Drug Research: Used in the development of next-generation antiviral agents, particularly for DNA viruses.
• Anticancer Agent Development: Serves as a building block for creating prodrugs and targeted chemotherapeutic compounds.
• Biochemical Research: Employed in studies of enzyme inhibition, DNA/RNA interaction, and cellular metabolism pathways.
• Prodrug Synthesis: Utilized in the design of masked nucleoside derivatives to improve bioavailability and targeting.
• Medicinal Chemistry: A versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.

Basic Information

Item	Details
Product Name	1Alpha-Deoxy-1Alpha-Azido-4Alpha-Deoxy-4Alpha-(Thymin-1-Yl)-2,3Alpha:2Alpha,5Alpha-Dianhydro-L-Altritol
CAS No.	900513-69-1
Molecular Formula	C12H14N6O5
Molecular Weight	322.28 g/mol
Synonyms	1-Deoxy-1-azido-4-deoxy-4-(thymin-1-yl)-2,3:2,5-dianhydro-L-altritol; 1-Azido-1,4-dideoxy-4-(thymin-1-yl)-2,3:2,5-dianhydro-L-altritol; Dianhydroaltritol thymine azide derivative; L-Altritol, 1-deoxy-1-azido-4-deoxy-4-(thymin-1-yl)-2,3:2,5-dianhydro-; Nucleoside analogue intermediate; Thyminyl dianhydroaltritol azide
EINECS	Contact for details

Quality Control

Our 1Alpha-Deoxy-1Alpha-Azido-4Alpha-Deoxy-4Alpha-(Thymin-1-Yl)-2,3Alpha:2Alpha,5Alpha-Dianhydro-L-Altritol is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency suitable for research and development. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP guidelines where applicable, and our quality systems are designed to meet the stringent requirements of pharmaceutical intermediate supply.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C under an inert atmosphere (e.g., nitrogen or argon) to prevent oxidation. The container should be kept in a cool, dry, well-ventilated area, separate from incompatible materials. For long-term storage, desiccants are recommended.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.