Description

(4-Amino-2-Trifluoromethyl-Phenyl)-Methanol is a versatile aromatic amine alcohol building block characterized by its trifluoromethyl and amino functional groups. This compound is critical for the synthesis of advanced pharmaceutical intermediates and agrochemicals, where its unique structure imparts desirable properties like metabolic stability and lipophilicity. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a building block for advanced electronic materials, including liquid crystal displays (LCDs) and organic light-emitting diodes (OLEDs).
• Polymer & Resin Modifier: Incorporated into specialty polymers to modify thermal stability, chemical resistance, and surface properties.
• Dye & Pigment Manufacturing: Acts as an intermediate in the production of complex dyes and high-performance pigments.
• Cross-coupling Reactions: A valuable substrate in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) for constructing complex biaryl structures.
• Research & Development: Essential for academic and industrial research in medicinal chemistry and material science for exploring new chemical entities.

Basic Information

Product Name	(4-Amino-2-Trifluoromethyl-Phenyl)-Methanol
CAS No.	900254-46-8
Molecular Formula	C8H8F3NO
Molecular Weight	191.15 g/mol
Synonyms	2-(Trifluoromethyl)-4-aminobenzyl alcohol; 4-Amino-α-(trifluoromethyl)benzenemethanol; (4-Amino-2-trifluoromethylphenyl)methanol; 2-(Trifluoromethyl)-4-aminophenylmethanol; 4-Amino-2-(trifluoromethyl)benzyl alcohol; Benzenemethanol, 4-amino-α-(trifluoromethyl)-; 4-Amino-2-trifluoromethylbenzyl alcohol
EINECS	Contact for details

Quality Control

Our (4-Amino-2-Trifluoromethyl-Phenyl)-Methanol is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) with detailed specifications are provided for each shipment, ensuring traceability and consistency for our customers' critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent oxidation and absorption of moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.