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Carbamylated Triiodothyronine CAS NO 99780-73-1
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CAS No.:99780-73-1
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
Carbamylated Triiodothyronine is a chemically modified derivative of the thyroid hormone triiodothyronine (T3). This compound is of significant interest in biochemical and pharmaceutical research, particularly for studying hormone-receptor interactions and metabolic pathways. It serves as a critical reference standard and intermediate for researchers and manufacturers in the fields of endocrinology, diagnostic assay development, and advanced pharmaceutical synthesis.
Application
- Biochemical Research: Used as a reference compound and molecular probe for studying thyroid hormone action, receptor binding affinity, and signal transduction mechanisms.
- Diagnostic Development: Serves as a key antigen or calibrator in the development and validation of immunoassays for thyroid function testing.
- Pharmaceutical Intermediates: Acts as a sophisticated synthetic intermediate in the research and development of novel thyroid hormone analogs and related therapeutic agents.
- Metabolic Studies: Employed in in vitro and in vivo studies to investigate the effects of hormone modification on metabolic rate, gene expression, and protein synthesis.
- Quality Control Standards: Utilized as a high-purity certified reference material (CRM) to ensure accuracy and consistency in analytical laboratories.
Basic Information
| Product Name | Carbamylated Triiodothyronine |
| CAS No. | 99780-73-1 |
| Molecular Formula | C16H13I3N2O5 |
| Molecular Weight | 725.99 g/mol |
| Synonyms | 3,3',5-Triiodothyronine Carbamate; T3 Carbamate; Carbamoyl-T3; O-Carbamoyl-3,3',5-triiodothyronine; 4-(4-Hydroxy-3-iodophenoxy)-3,5-diiodophenylcarbamic acid; Thyroid Hormone T3 Derivative; L-Thyronine, O-carbamoyl-3,3',5-triiodo- |
| EINECS | Contact for details |
Quality Control
Our Carbamylated Triiodothyronine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, spectroscopic identification, and residual solvent analysis, to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and conformance to specifications.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccated conditions.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white powder |
| Identification (IR) | Conforms to structure |
| Purity (HPLC) | ≥ 98.0% |
| Water Content (KF) | ≤ 2.0% |
| Residual Solvents (GC) | Meets ICH guidelines |
| Heavy Metals | < 20 ppm |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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