Description

3-Monoiodothyronine is a key iodinated aromatic amino acid derivative, serving as a crucial intermediate in the synthesis of thyroid hormones and related analogs. Its precise chemical structure makes it an essential building block for pharmaceutical research and development, particularly in endocrinology and metabolic studies. This compound is primarily utilized by research institutions, pharmaceutical manufacturers, and fine chemical synthesis specialists focused on hormone-related therapeutics and diagnostic agents.

Application

• Pharmaceutical Intermediate: Critical precursor in the synthesis of thyroid hormone analogs (e.g., liothyronine) and related active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a reference standard and probe in studies of thyroid hormone metabolism, receptor binding, and transport mechanisms.
• Diagnostic Agent Development: Serves as a starting material for developing radiolabeled compounds (e.g., with I-125 or I-131) used in diagnostic imaging and assays.
• Endocrinology Studies: Employed in in vitro and in vivo research to investigate the structure-activity relationships of iodothyronines.
• Fine Chemical Synthesis: A valuable building block for organic chemists creating novel iodinated aromatic compounds for various applications.

Basic Information

Product Name	3-Monoiodothyronine
CAS No.	16170-92-6
Molecular Formula	C15H14INO4
Molecular Weight	423.18 g/mol
Synonyms	3-Monoidothyronine; 3-T1; 3-Iodothyronine; O-(4-Hydroxy-3-iodophenyl)-3,5-diiodo-L-tyrosine; 3-Iodo-L-thyronine; L-3-Iodothyronine; 3'-Monoiodo-L-thyronine; 3'-T1
EINECS	Contact for details

Quality Control

Our 3-Monoiodothyronine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and pharmaceutical applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting purity, related substances, and residual solvents.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) to minimize oxidation and degradation. The container should be kept in a cool, dry, and well-ventilated area, away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines
Heavy Metals	≤ 20 ppm
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.