Description

3,5-Diiodo-L-Thyronine is a key iodinated derivative of the thyroid hormone thyronine, serving as a crucial intermediate in the synthesis of more complex thyroid hormone analogs and metabolites. This compound is of significant value in biochemical and pharmaceutical research for studying thyroid hormone metabolism, receptor binding, and structure-activity relationships. It is primarily needed by research institutions, pharmaceutical development laboratories, and fine chemical manufacturers focused on endocrinology, metabolic disorder research, and the production of reference standards.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of thyroid hormone analogs and potential therapeutic agents for metabolic disorders.
• Biochemical Research: Used as a reference standard and probe in studies of thyroid hormone action, deiodinase enzyme activity, and metabolic pathways.
• Endocrinology Studies: Essential for in vitro and in vivo research investigating the mechanisms of thyroid function and hormone regulation.
• Diagnostic Agent Development: Serves as a precursor or standard in the development of diagnostic kits and assays related to thyroid function.
• Academic Research: Utilized in university and institutional labs for fundamental research in hormone chemistry and cell signaling.
• Fine Chemical Synthesis: Employed in custom synthesis and the production of specialized, high-value chemical entities for advanced research applications.

Basic Information

Product Name	3,5-Diiodo-L-Thyronine
CAS No.	1041-01-6
Molecular Formula	C15H13I2NO4
Molecular Weight	525.08 g/mol
Synonyms	3,5-Diiodothyronine; T2; 3,5-T2; 3,5-Diiodo-L-thyronine; O-(4-Hydroxy-3,5-diiodophenyl)-3,5-diiodo-L-tyrosine; 3,5-Diiodo-4-(4-hydroxy-3,5-diiodophenoxy)phenylalanine; L-3,5-Diiodothyronine; 3,5-Diiodo-L-thyronine
EINECS	213-876-8

Quality Control

Our 3,5-Diiodo-L-Thyronine is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets high-purity standards suitable for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the product under an inert atmosphere for long-term stability and to minimize degradation. Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.