Description

Liothyronine Sodium is the sodium salt of the active thyroid hormone triiodothyronine (T3). This high-purity pharmaceutical active ingredient is critical for precise hormone replacement therapy and advanced biochemical research. It is primarily required by pharmaceutical manufacturers for the production of thyroid medications and by research institutions for metabolic and endocrine studies.

Application

• Pharmaceutical Formulations: Active pharmaceutical ingredient (API) in tablets and capsules for the treatment of hypothyroidism and thyroid hormone replacement therapy.
• Diagnostic & Research Use: Critical standard and reagent in clinical diagnostics, radioimmunoassays (RIA), and enzyme-linked immunosorbent assays (ELISA) for thyroid function testing.
• Biochemical Research: Essential tool for studying cellular metabolism, gene expression regulation, mitochondrial function, and the mechanisms of thyroid hormone action in vitro and in vivo.
• Reference Standard: Used as a certified reference material (CRM) for quality control and method validation in analytical laboratories.
• Veterinary Medicine: Component in treatments for thyroid disorders in companion animals and livestock.

Basic Information

Product Name	Liothyronine Sodium
CAS No.	55-06-1
Molecular Formula	C15H11I3NNaO4
Molecular Weight	672.96 g/mol
Synonyms	L-Triiodothyronine Sodium Salt; T3 Sodium Salt; 3,3',5-Triiodo-L-thyronine Sodium Salt; Thyronine, 3,3',5-triiodo-, sodium salt; Sodium Liothyronine; Triiodothyronine Sodium; O-(4-Hydroxy-3-iodophenyl)-3,5-diiodo-L-tyrosine Sodium Salt; Cytomel (Brand Name)
EINECS	200-221-5

Quality Control

Our Liothyronine Sodium is manufactured and tested under strict quality management systems. It meets high-purity standards suitable for pharmaceutical and research applications, with specifications aligning with major pharmacopoeial guidelines. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each batch to ensure traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to standard
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0% (on anhydrous basis)
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.