Description

Thyronine is a key iodinated aromatic amino acid derivative, serving as a fundamental building block in organic synthesis and biochemical research. Its structural significance lies in its role as a precursor to thyroid hormones and related bioactive compounds, making it essential for studies in endocrinology and metabolic pathways. This high-purity intermediate is primarily sought by the pharmaceutical, biotechnology, and advanced chemical synthesis sectors for the development of novel therapeutics and diagnostic agents.

Application

• Pharmaceutical Intermediate: Critical precursor in the synthesis of thyroid hormone analogs (e.g., Levothyroxine) and related active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a standard or reagent in metabolic studies, hormone receptor binding assays, and endocrine system research.
• Organic Synthesis: Serves as a versatile building block for constructing complex molecules in medicinal chemistry and fine chemical production.
• Diagnostic Agent Development: Employed in the research and development of radio-labeled compounds and assays for thyroid function testing.
• Reference Standard: Utilized as a high-purity analytical standard in quality control laboratories for HPLC, LC-MS, and other chromatographic methods.

Basic Information

Product Name	Thyronine
CAS No.	101-66-6
Molecular Formula	C15H15NO4
Molecular Weight	273.28 g/mol
Synonyms	O-(4-Hydroxyphenyl)-3,5-diiodo-L-tyrosine; 3,5-Diiodothyronine; 3,5-Diiodo-L-tyrosine O4-phenyl ether; 4-(4-Hydroxyphenoxy)-3,5-diiodo-L-phenylalanine; DIT; DITh; Thyronine base
EINECS	202-966-5

Quality Control

Our Thyronine is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR for identification, and residual solvent analysis, to ensure it meets exacting standards suitable for pharmaceutical research. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with specified parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to handle under an inert atmosphere for long-term storage and to minimize headspace in opened containers to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.