Description

Calcitonin, Salmon, Gly(8)-Des-Leu(16)-Arg(24)- CAS NO 115888-20-5 is a synthetic analogue of salmon calcitonin, a polypeptide hormone with a specific amino acid sequence modification designed to enhance its stability and biological activity. This engineered peptide is critical for research and development in the pharmaceutical and biotechnology sectors, offering a more stable and potent alternative to native calcitonin for therapeutic studies. It is primarily utilized by researchers and manufacturers focused on metabolic bone disorders, such as osteoporosis and Paget's disease, as well as in the development of novel peptide-based therapeutics and diagnostic assays.

Application

• Pharmaceutical Research & Development: As a key reference standard and active ingredient in preclinical and clinical studies for bone metabolism regulation.
• Therapeutic Agent Development: For formulating potential treatments for osteoporosis, hypercalcemia, and Paget's disease of bone.
• Biochemical Research: Used in studies investigating calcium homeostasis, osteoclast activity, and peptide hormone receptor interactions.
• Diagnostic Manufacturing: Serves as a critical component in the production of calibration standards and reagents for immunoassays and clinical diagnostic kits.
• Academic & Institutional Studies: Employed in university and research institute laboratories for fundamental endocrinology and pharmacology research.
• Peptide Chemistry Studies: As a model compound for studying structure-activity relationships (SAR) and the stability of modified peptide hormones.

Basic Information

Product Name	Calcitonin, Salmon, Gly(8)-Des-Leu(16)-Arg(24)- CAS NO 115888-20-5
CAS No.	115888-20-5
Molecular Formula	C₁₄₈H₂₄₄N₄₄O₄₇S₂
Molecular Weight	~3431.9 g/mol
Synonyms	Salmon Calcitonin (8-Glycine, 16-Des-Leucine, 24-Arginine) Analogue; [Gly8, des-Leu16, Arg24]-Salmon Calcitonin; Gly8-des-Leu16-Arg24-SCT; Calcitonin Salmon Gly8 des-Leu16 Arg24; SCT Analogue; Calcitonin (salmon) fragment 1-32, 8-glycine-16-des-leucine-24-arginine-; H-Cys-Ser-Asn-Leu-Ser-Thr-Cys-Val-Leu-Gly-Lys-Leu-Ser-Gln-Glu-Leu-His-Lys-Leu-Gln-Thr-Tyr-Pro-Arg-Thr-Asn-Thr-Gly-Ser-Gly-Thr-Pro-NH₂ (Disulfide bridge: 1-7)
EINECS	Contact for details

Quality Control

Our Calcitonin, Salmon, Gly(8)-Des-Leu(16)-Arg(24)- is produced and tested under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and peptide content, mass spectrometry for identity confirmation, and tests for related substances and residual solvents. We provide comprehensive Certificates of Analysis (COA) detailing all specifications to ensure compliance with research and development requirements. Our commitment is to deliver high-purity, consistent peptide materials to support your critical work.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature before opening to minimize moisture uptake. For long-term storage, keep desiccated.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Peptide Content (UV)	≥ 80.0%
Single Impurity (HPLC)	≤ 2.0%
Total Impurities (HPLC)	≤ 5.0%
Amino Acid Analysis	Within ±10% of theoretical
Water Content (KF)	≤ 8.0%
Acetate Content (HPLC/IC)	≤ 15.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.