Description

4-Azidoclonidine is a specialized chemical derivative of the α-2 adrenergic receptor agonist clonidine, distinguished by the introduction of an azido functional group. This modification makes it a valuable tool compound for biochemical research, particularly in the study of receptor structure, function, and ligand interactions. It is primarily utilized by pharmaceutical R&D departments, academic research institutions, and biotechnology companies engaged in neuroscience and cardiovascular research. The compound's unique structure facilitates advanced research applications such as photoaffinity labeling and molecular probe development.

Application

• Photoaffinity Labeling Probe: Used to covalently tag and study α-2 adrenergic receptors and related proteins in biological systems.
• Biochemical Research Reagent: Serves as a key intermediate or tool compound for investigating adrenergic signaling pathways.
• Medicinal Chemistry Intermediate: Employed in the synthesis and development of novel receptor ligands and potential therapeutic agents.
• Neuroscience Studies: Applied in research focused on understanding the modulation of neurotransmitter release and autonomic functions.
• Molecular Biology Applications: Utilized in the creation of probes for receptor localization and characterization studies.
• High-Throughput Screening (HTS): Can be used as a reference compound or competitor in assay development for drug discovery programs.

Basic Information

Product Name	4-Azidoclonidine
CAS No.	99616-15-6
Molecular Formula	C9H9ClN6
Molecular Weight	236.67 g/mol
Synonyms	4-Azidoclonidine; N-(2,6-Dichlorophenyl)-4-azido-2-imidazolidinylideneamine; 4-Azido-2-((2,6-dichlorophenyl)imino)imidazolidine; Azidoclonidine; Clonidine azide analog; 2-[(2,6-Dichlorophenyl)imino]-4-azidoimidazolidine
EINECS	Contact for details

Quality Control

Our 4-Azidoclonidine is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity, suitable for sensitive research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity determination and spectroscopic methods for structural confirmation. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all relevant specifications and test results to support your quality assurance processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Keep the container sealed to protect this light-sensitive material from degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.