Description

Sertaconazole Nitrate is a potent synthetic antifungal agent belonging to the imidazole class. Its primary value lies in its broad-spectrum activity against dermatophytes, yeasts, and molds, making it a critical active pharmaceutical ingredient (API). This compound is essential for manufacturers in the pharmaceutical and personal care industries developing topical antifungal treatments for conditions like athlete's foot, ringworm, and cutaneous candidiasis.

Application

• Pharmaceutical API: Primary use as the active ingredient in prescription and over-the-counter (OTC) topical antifungal creams, ointments, powders, and sprays.
• Dermatological Formulations: Key component in medicated products for treating tinea pedis (athlete's foot), tinea corporis (ringworm), tinea cruris (jock itch), and cutaneous yeast infections.
• Veterinary Medicine: Incorporated into topical preparations for treating fungal skin infections in companion animals and livestock.
• Cosmaceutical Products: Used in specialized foot care products, antifungal soaps, and medicated shampoos for dandruff caused by Malassezia yeast.
• Research & Development: Serves as a reference standard and building block in antimicrobial research and the development of new antifungal agents.

Basic Information

Product Name	Sertaconazole Nitrate
CAS No.	99592-39-9
Molecular Formula	C₂₀H₁₅Cl₃N₂O₃S
Molecular Weight	469.77 g/mol
Synonyms	1-[2-(7-Chloro-1-benzothiophen-3-yl)methoxy]-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole nitrate; Sertaconazole mononitrate; FI-7045; Dermofix; Zalain; Zertanol; Zertaconazole; Tosedon
EINECS	Contact for details

Quality Control

Our Sertaconazole Nitrate is manufactured under strict quality management systems, targeting compliance with major pharmacopoeial standards such as USP and EP. Every batch undergoes comprehensive analytical testing including identification, assay, impurity profiling, and residual solvent analysis to ensure it meets stringent pharmaceutical-grade specifications. A Certificate of Analysis (COA) documenting all test results is provided with each shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to almost white crystalline powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity: ≤ 0.5% Total impurities: ≤ 1.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.