Description

7-Benzofurancarbonyl Chloride, 5-Chloro- (9Ci) is a high-purity, reactive benzofuran derivative, specifically a functionalized acid chloride. This compound serves as a critical pharmaceutical intermediate and organic synthesis building block, enabling the introduction of the 5-chlorobenzofuran moiety into more complex molecular architectures. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require precise and reliable synthetic precursors for developing active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the benzofuran scaffold contributes to biological activity.
• Organic Light-Emitting Diodes (OLEDs): Acts as a precursor for electron-transport materials or emitting layer components in electronic display technologies.
• Material Science Research: Employed in the development of polymers, liquid crystals, and other functional materials with specific optical or electronic properties.
• Chemical Research & Development: A versatile reagent for academic and industrial R&D labs exploring new reactions, catalysis, and the creation of compound libraries.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specified target molecules.

Basic Information

Product Name	7-Benzofurancarbonyl Chloride, 5-Chloro- (9Ci)
CAS No.	99517-27-8
Molecular Formula	C9H4Cl2O2
Molecular Weight	215.03 g/mol
Synonyms	5-Chloro-7-benzofurancarbonyl chloride; 5-Chloro-1-benzofuran-7-carbonyl chloride; 5-Chlorobenzofuran-7-carbonyl chloride; 5-Chloro-7-carboxybenzofuran chloride; 7-Carboxy-5-chlorobenzofuran chloride
EINECS	Contact for details

Quality Control

Our production of 7-Benzofurancarbonyl Chloride, 5-Chloro- (9Ci) adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including HPLC, GC, and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment, supporting compliance in GMP-aligned synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.