Description

(E)-3-Ethoxyacryloyl Chloride is a versatile and highly reactive acid chloride derivative used as a key building block in organic synthesis. Its primary value lies in its ability to efficiently introduce the (E)-3-ethoxyacryloyl moiety into target molecules, facilitating the construction of complex chemical architectures. This intermediate is particularly valuable for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries engaged in developing active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of various active pharmaceutical ingredients (APIs), including potential kinase inhibitors and other therapeutic agents.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where its reactive group enables the creation of novel bioactive compounds.
• Fine Chemical Production: Serves as a precursor for dyes, pigments, and specialty polymers that require the incorporation of specific acryloyl functionalities.
• Material Science Research: Employed in the development of novel monomers and cross-linking agents for advanced polymeric materials.
• Chemical Biology Probes: Useful for modifying peptides, proteins, or other biomolecules to study biological processes or create conjugates.

Basic Information

Product Name	(E)-3-Ethoxyacryloyl Chloride
CAS No.	99471-66-6
Molecular Formula	C5H7ClO2
Molecular Weight	134.56 g/mol
Synonyms	trans-3-Ethoxyacryloyl Chloride; (E)-3-Ethoxy-2-propenoyl Chloride; 3-Ethoxyacrylic Acid Chloride; (E)-3-Ethoxyacrylic Acid Chloride; 2-Propenoyl chloride, 3-ethoxy-, (E)-; Ethoxyacryloyl Chloride; NSC 403820
EINECS	Contact for details

Quality Control

Our (E)-3-Ethoxyacryloyl Chloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including assay by GC/HPLC and impurity profiling, to ensure high purity and consistency. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from strong bases, oxidizers, and sources of ignition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.