Description

3'-Amino-3'-Deoxyadenosine-3',5'-Cyclic Monophosphate Sodium Salt is a chemically modified derivative of cyclic adenosine monophosphate (cAMP), a fundamental secondary messenger in cellular signaling. This compound is valued for its enhanced stability and specific inhibitory effects on cAMP-dependent protein kinase (PKA), making it a critical tool for probing intracellular signaling pathways. It is primarily utilized by researchers and developers in the fields of biochemical research, pharmaceutical development, and molecular biology to study cellular regulation and develop targeted therapeutic strategies.

Application

• Biochemical Research: As a potent and specific inhibitor of Protein Kinase A (PKA) for studying cAMP-mediated signal transduction pathways.
• Pharmaceutical R&D: Used as a reference standard and a key intermediate in the development of novel therapeutics targeting cellular signaling disorders.
• Cell Biology Studies: Employed to investigate the role of cAMP in cellular processes such as metabolism, gene expression, and cell proliferation.
• Enzyme Kinetics: Serves as a substrate analog in enzymatic studies to understand the mechanism of phosphodiesterases and kinases.
• Diagnostic Reagent Manufacturing: A potential component in the formulation of diagnostic kits for research and clinical analysis.

Basic Information

Item	Details
Product Name	3'-Amino-3'-Deoxyadenosine-3',5'-Cyclic Monophosphate Sodium Salt
CAS No.	99443-14-8
Molecular Formula	C10H12N6O5PNa
Molecular Weight	350.20 g/mol
Synonyms	3'-NH2-3'-dA-cAMP Sodium Salt; 3'-Amino-3'-deoxy-cAMP Sodium Salt; Rp-3'-Amino-3'-deoxyadenosine-3',5'-cyclic monophosphorothioate Sodium Salt (related analog); 3'-Amino-cAMP Na; cAMP 3'-amino-3'-deoxy analog sodium salt; Adenosine, 3'-amino-3'-deoxy-, 3',5'-(hydrogen phosphate) sodium salt; 3'-Amino-3'-deoxyadenosine cyclic 3',5'-(hydrogen phosphate) sodium salt
EINECS	Contact for details

Quality Control

Our 3'-Amino-3'-Deoxyadenosine-3',5'-Cyclic Monophosphate Sodium Salt is manufactured under strict quality systems to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to rigorous in-house standards to meet the demanding requirements of pharmaceutical research and analytical reference material production.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the container to reach room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines
Biological Activity	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.