Description

D-Threo-Hexaroyl Dichloride, 2,5-Anhydro-3,4-Dideoxy- (9Ci) is a specialized, high-purity chemical intermediate characterized by its reactive dichloride functional group. This compound matters for its role as a critical building block in the synthesis of complex, optically active molecules, enabling precise control over stereochemistry. It is primarily needed by research institutions and pharmaceutical development teams working on novel active pharmaceutical ingredients (APIs), nucleoside analogs, and advanced fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of nucleoside-based therapeutics and other stereochemically defined APIs.
• Organic Synthesis Building Block: Used in acyl chloride coupling reactions to introduce the D-threo-hexaroyl moiety into complex molecular architectures.
• Biochemical Research: Employed in the synthesis of labeled compounds, probes, and substrates for enzymatic and metabolic studies.
• Fine Chemical Production: Serves as a precursor in the manufacture of specialty chemicals requiring specific anhydro-dideoxy sugar derivatives.
• Academic & R&D Laboratories: Utilized in methodological development and the exploration of new synthetic pathways in carbohydrate and medicinal chemistry.

Basic Information

Product Name	D-Threo-Hexaroyl Dichloride, 2,5-Anhydro-3,4-Dideoxy- (9Ci)
CAS No.	99340-08-6
Molecular Formula	C6H6Cl2O2
Molecular Weight	181.02 g/mol
Synonyms	2,5-Anhydro-3,4-dideoxy-D-threo-hexaroyl dichloride; D-threo-2,5-Anhydro-3,4-dideoxy-hexaroyl dichloride; Hexaroyl dichloride, 2,5-anhydro-3,4-dideoxy-D-threo-; (2R,3S)-2,5-Anhydro-3,4-dideoxyhexaroyl dichloride; NSC 339063; 2,5-Anhydro-3,4-dideoxy-D-threo-hexaric acid dichloride
EINECS	Contact for details

Quality Control

Our D-Threo-Hexaroyl Dichloride is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity, essential for sensitive synthetic applications. All materials are accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support cGMP and ISO-aligned practices for research and development use, with specifications available to meet your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its nature as a strong acid/organic solvent, keep away from heat, sparks, open flames, and incompatible materials such as bases, alcohols, and amines. Handle and store under an inert atmosphere (e.g., nitrogen or argon) if specified for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Chiral Purity	≥ 99.0% ee

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.