Description

2H-Pyran-4-Carbonyl Chloride, 3,6-Dihydro- (9Ci) is a versatile and highly reactive chemical intermediate, essential for constructing complex molecular architectures. Its core value lies in its carbonyl chloride functional group, which readily undergoes nucleophilic acyl substitution reactions, making it a critical building block for advanced synthesis. This compound is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, particularly in the development of heterocyclic compounds with potential biological activity.
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and fungicides, where the pyran moiety can contribute to specific modes of action.
• Material Science Precursor: Serves as a monomer or cross-linking agent in the development of specialized polymers, resins, and coatings with tailored properties.
• Organic Synthesis Building Block: Employed in academic and industrial R&D for constructing complex natural product analogs, ligands, and other fine chemicals.
• Chemical Derivatization: Useful for introducing the 3,6-dihydro-2H-pyran-4-carbonyl moiety into target molecules to modify solubility, bioavailability, or reactivity.

Basic Information

Product Name	2H-Pyran-4-Carbonyl Chloride, 3,6-Dihydro- (9Ci)
CAS No.	99338-34-8
Molecular Formula	C6H7ClO2
Molecular Weight	146.57 g/mol
Synonyms	3,6-Dihydro-2H-pyran-4-carbonyl chloride; 4-Chlorocarbonyl-3,6-dihydro-2H-pyran; DHP-COCl; Tetrahydro-4-pyrancarbonyl chloride (related); 3,4-Dihydro-2H-pyran-6-carbonyl chloride (tautomer); 3,6-Dihydro-2H-pyran-4-carboxylic acid chloride; 4-Pyrancarbonyl chloride, 3,6-dihydro-
EINECS	Contact for details

Quality Control

Our production of 2H-Pyran-4-Carbonyl Chloride, 3,6-Dihydro- (9Ci) adheres to stringent quality protocols to ensure batch-to-batch consistency and reliability for your critical syntheses. Each lot is subjected to comprehensive analytical testing, including assay, purity profiling, and identification. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to support your quality management systems and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic and highly volatile nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Purity (GC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.