Description

Saquayamycin C is a potent ansamycin-class antibiotic and antitumor agent derived from microbial fermentation. This compound is valued for its significant biological activity, particularly as a topoisomerase II inhibitor and DNA intercalator, making it a crucial tool in biochemical research and drug discovery. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and biotechnology companies focused on oncology and antimicrobial development.

Application

• Pharmaceutical Research & Development: Serves as a key reference standard and active pharmaceutical ingredient (API) intermediate in the development of novel anticancer and antimicrobial therapies.
• Biochemical Mechanism Studies: Used as a specific inhibitor to study DNA replication, transcription processes, and the function of topoisomerase enzymes in cellular models.
• Antitumor Activity Screening: Employed in in vitro and in vivo assays to evaluate cytotoxicity and antitumor efficacy against various cancer cell lines.
• Microbiology Research: Investigated for its potent activity against Gram-positive bacteria and its role in understanding antibiotic resistance mechanisms.
• Academic & Institutional Research: A critical reagent for universities and research institutes conducting studies in medicinal chemistry, molecular biology, and pharmacology.

Basic Information

Item	Details
Product Name	Saquayamycin C
CAS No.	99260-70-5
Molecular Formula	C39H48N2O12
Molecular Weight	736.81 g/mol
Synonyms	Saquayamycin C; Antibiotic BMY-28438; BMY 28438; NSC-658600; 5,12-Dideoxy-6-O-methyl-12-oxo-6a,12a-didehydro-6H,12H-naphtho[2,3-b]pyrano[3,2-e]isoquinoline-2,8,9,13-tetrol, 4-[(2S,4S,5S)-4,5-dihydroxy-6-methyl-2-(methylamino)tetrahydro-2H-pyran-2-yl]-10-[(2R,5S)-5-ethyl-5,6-dihydro-2H-pyran-2-yl]-1,3,11-trimethoxy-
EINECS	Contact for details

Quality Control

Every batch of Saquayamycin C is manufactured and analyzed under strict quality management systems. We provide comprehensive Certificates of Analysis (COA) that detail purity, identity, and impurity profiles, ensuring traceability and compliance with research-grade standards. Our quality commitment supports reliable and reproducible results for your critical research applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. For short-term use, the product may be stored at 2-8°C. Allow the vial to equilibrate to room temperature before opening to minimize moisture condensation. Keep the container in a dry, well-ventilated area.

Specification

Item	Specification
Appearance	Yellow to orange powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.