Description

Saquayamycin B1 CAS NO 99260-68-1 is a specialized ansamycin-class antibiotic compound derived from microbial fermentation. This product is valued for its potent biological activity, particularly as a key intermediate and reference standard in advanced pharmaceutical research and development. It is primarily utilized by biotechnology firms, academic research institutions, and pharmaceutical companies engaged in the discovery of novel anti-infective and anti-cancer agents.

Application

• Pharmaceutical Research & Development: Serves as a critical reference standard and building block in the synthesis and study of novel ansamycin derivatives.
• Antibiotic Mechanism Studies: Used in biochemical assays to investigate bacterial RNA polymerase inhibition and related pathways.
• Oncology Research: Employed as a tool compound in preclinical studies to evaluate anti-proliferative effects against various cancer cell lines.
• Microbial Genetics: Utilized in research exploring bacterial resistance mechanisms and the biosynthesis of complex natural products.
• Biochemical Reagent: Functions as a high-purity biochemical reagent for enzymatic and cell-based screening assays in drug discovery.

Basic Information

Product Name	Saquayamycin B1
CAS No.	99260-68-1
Molecular Formula	C39H48N2O12
Molecular Weight	736.81 g/mol
Synonyms	Saquayamycin B1; Antibiotic BMY-28438; BMY 28438; BMY-28438; Saquayamycin B; (8S,9S,10R,11R,13S,14R,16R,18S)-18-[(2S,4S,5S)-4,5-Dihydroxy-6-methyloxan-2-yl]oxy-8,10,11,13,14,16-hexahydroxy-9,11-dimethyl-6,15-dioxo-5,7-dioxapentacyclo[10.8.0.02,9.03,7.014,18]icosa-1(12),2,4,17,19-pentaen-19-yl carbamate
EINECS	Contact for details

Quality Control

Our Saquayamycin B1 is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and high purity for research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity determination and spectroscopic methods for structural confirmation. A Certificate of Analysis (COA) detailing all relevant specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dedicated freezer. The product is hygroscopic (moisture-sensitive); ensure the container is sealed under an inert atmosphere after each use to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	Yellow to orange powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.