Description

Saquayamycin is a potent ansamycin-class antibiotic compound, identified by CAS NO 99260-65-8, known for its significant biological activity. This compound serves as a crucial intermediate and reference standard in advanced pharmaceutical research and development. It is primarily utilized by research institutions and pharmaceutical companies focused on oncology and antimicrobial drug discovery.

Application

• Pharmaceutical Research: As a key reference standard and active pharmaceutical ingredient (API) intermediate in the development of novel anticancer and antibiotic therapies.
• Biochemical Studies: For investigating mechanisms of action involving DNA intercalation and topoisomerase inhibition in cellular models.
• Academic Research: Utilized in university and institutional labs for studying the structure-activity relationships (SAR) of ansamycin antibiotics.
• Pre-clinical Development: Serves as a lead compound or a benchmark in screening assays for evaluating new therapeutic candidates.

Basic Information

Product Name	Saquayamycin
CAS No.	99260-65-8
Molecular Formula	C39H48N2O11
Molecular Weight	720.81 g/mol
Synonyms	Saquayamycin A; Antibiotic SA 300A; NSC 654836; 3,4,6,8,10,12,14,16,18,20-Decahydro-3,5,10,13,19-pentahydroxy-4,9,14,18-tetramethyl-8,15-bis(1-methylethyl)-1,22-dioxo-2,21-dioxa-7,16-diazatetracyclo[15.7.0.05,24.011,23]tetracosa-11,13,23-triene-17-carboxylic acid, (3R,4S,5S,8R,9R,10S,11E,13E,15S,16R,18R,19R)-
EINECS	Contact for details

Quality Control

Our Saquayamycin is produced under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant standards for research-grade chemicals to support your critical development work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	Yellow to brownish powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.