Description

Donetidine is a high-purity pharmaceutical intermediate with the CAS registry number 99248-32-5. This compound is valued for its critical role in the synthesis of advanced active pharmaceutical ingredients (APIs), where consistent quality and reliable supply are paramount. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and fine chemical industries.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel therapeutic agents and active pharmaceutical ingredients (APIs).
• Chemical Research & Development: Serves as a crucial reagent in medicinal chemistry for the discovery and optimization of new drug candidates.
• Fine Chemical Synthesis: Used in multi-step organic synthesis to introduce specific functional groups into complex molecular structures.
• Contract Manufacturing (CMO): Supplied to contract manufacturing organizations for the production of clinical trial materials and commercial drug substances.

Basic Information

Product Name	Donetidine
CAS No.	99248-32-5
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Donetidine; 99248-32-5; 1,3-Dihydro-2H-imidazo[4,5-b]pyridin-2-one, 1-(4-fluorophenyl)methyl]- (IUPAC); UNII-7S8K385E0F; 1-[(4-Fluorophenyl)methyl]-1,3-dihydro-2H-imidazo[4,5-b]pyridin-2-one
EINECS	Contact for details

Quality Control

Our Donetidine is manufactured under strict quality management systems to ensure it meets the high standards required for pharmaceutical applications. Each batch undergoes comprehensive analytical testing, including identity confirmation, purity assay, and impurity profiling. Certificates of Analysis (COA) documenting full compliance with agreed specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.