Description

Pibutidine CAS NO 103922-33-4 is a selective histamine H2-receptor antagonist. This compound is a key pharmaceutical intermediate in the synthesis of advanced therapeutic agents targeting gastric acid secretion. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development and production of gastrointestinal medications. Our supply ensures high purity and consistent quality for critical R&D and manufacturing processes.

Application

• Pharmaceutical Intermediate: Primary use in the synthesis of gastroprotective drugs and H2-antagonists.
• Research & Development: Serves as a reference standard and building block in medicinal chemistry for novel therapeutic discovery.
• Active Pharmaceutical Ingredient (API) Manufacturing: Used in the controlled production of finished dosage forms.
• Biochemical Research: Tool compound for studying histamine receptor pathways and related physiological mechanisms.
• Quality Control Laboratories: Employed as an analytical standard for method development and validation in pharmaceutical QC.

Basic Information

Item	Detail
Product Name	Pibutidine
CAS No.	103922-33-4
Molecular Formula	C17H23N3O3S
Molecular Weight	349.45 g/mol
Synonyms	Pibutidine Hydrochloride; YM-11170; 2-[[[2-[(Diaminomethylene)amino]-4-thiazolyl]methyl]thio]-N-(2-ethoxyethyl)-N-methylacetamide; 2-({[2-(Carbamimidamido)-1,3-thiazol-4-yl]methyl}sulfanyl)-N-(2-ethoxyethyl)-N-methylacetamide; UNII-3W6S8LQ948; 3W6S8LQ948; YM11170
EINECS	Contact for details

Quality Control

Our Pibutidine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and assay, identification by spectroscopic methods, and control of specified impurities. A Certificate of Analysis (COA) documenting full compliance with agreed specifications is provided with every shipment to ensure traceability and quality assurance for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity: ≤ 0.5% Total impurities: ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.