Description

Tenatoprazole CAS NO 113712-98-4 is a proton pump inhibitor (PPI) compound, a key intermediate in the synthesis of advanced pharmaceutical actives. It matters as a critical building block for developing next-generation anti-ulcer and gastroesophageal reflux disease (GERD) therapeutics, offering a pathway to more potent and longer-lasting medications. This high-purity intermediate is essential for pharmaceutical R&D laboratories, contract manufacturing organizations (CMOs), and API producers focused on innovative gastrointestinal treatments.

Application

• Pharmaceutical Intermediate: Primary use as a key synthetic precursor in the manufacture of Tenatoprazole-based active pharmaceutical ingredients (APIs).
• Research & Development: Serves as a critical reference standard and starting material in medicinal chemistry programs for novel proton pump inhibitors.
• Contract Synthesis: Used by CMOs and CDMOs for the custom synthesis of Tenatoprazole and its derivative compounds under cGMP conditions.
• Analytical Standard: Employed as a high-purity standard in HPLC, LC-MS, and NMR for method development, validation, and quality control testing.
• Preclinical Studies: Utilized in formulation development and pharmacokinetic/pharmacodynamic (PK/PD) studies for new drug candidates.

Basic Information

Item	Detail
Product Name	Tenatoprazole
CAS No.	113712-98-4
Molecular Formula	C₁₆H₁₈N₄O₃S
Molecular Weight	346.40 g/mol
Synonyms	TU-199; Tenatoprazole; 5-Methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole; 2-[[(4-Methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-5-methoxy-1H-benzimidazole; 5-Methoxy-2-(((4-methoxy-3,5-dimethyl-2-pyridinyl)methyl)sulfinyl)-1H-benzimidazole; Proton Pump Inhibitor Intermediate; TU199
EINECS	Contact for details

Quality Control

Our Tenatoprazole is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, residual solvent analysis, and identification by spectroscopic methods (IR, NMR), to ensure it meets exacting standards for pharmaceutical intermediate use. Certificates of Analysis (COA) detailing all test results are provided and can be tailored to meet specific client or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0% Any single impurity ≤0.5%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.