Description

Ebrotidine is a potent and selective histamine H₂-receptor antagonist. This compound is of significant interest in pharmaceutical research and development due to its potential therapeutic applications. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel gastrointestinal treatments and related pharmacological studies.

Application

• Pharmaceutical Research & Development: Serves as a key intermediate or active pharmaceutical ingredient (API) in the development of new anti-ulcer and gastroprotective medications.
• Biochemical Studies: Used as a reference standard or tool compound in pharmacological research to study histamine H₂-receptor mechanisms and signaling pathways.
• Preclinical Investigations: Employed in animal model studies to evaluate efficacy, pharmacokinetics, and safety profiles of potential drug candidates targeting acid-related disorders.
• Analytical Reference Material: Acts as a high-purity standard for quality control and method validation in analytical laboratories (HPLC, LC-MS).
• Chemical Synthesis: Functions as a sophisticated building block for the synthesis of more complex molecules or derivatives with modified biological activity.

Basic Information

Product Name	Ebrotidine
CAS No.	100981-43-9
Molecular Formula	C19H20N4O3S
Molecular Weight	384.45 g/mol
Synonyms	Ebroticine; N-[(E)-[[2-[[[2-[(Aminoiminomethyl)amino]-4-thiazolyl]methyl]thio]ethyl]amino]methylene]-4-bromobenzenesulfonamide; FI-3542; CAS 100981-43-9
EINECS	Contact for details

Quality Control

Our Ebrotidine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, detailing key parameters such as assay, related substances, and residual solvents.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.