Description

Leminoprazole CAS NO 104340-86-5 is a high-purity pharmaceutical intermediate belonging to the proton pump inhibitor (PPI) class, a critical building block in modern therapeutic development. Its primary value lies in its role as a key precursor for synthesizing advanced active pharmaceutical ingredients (APIs) targeting gastric acid-related disorders. This compound is essential for pharmaceutical manufacturers and contract research organizations (CROs) engaged in the development and production of next-generation gastroenterology treatments and novel drug formulations.

Application

• Active Pharmaceutical Ingredient (API) Synthesis: Primary use as a crucial intermediate in the manufacturing of proton pump inhibitor drugs.
• Pharmaceutical Research & Development: Serves as a reference standard and starting material in medicinal chemistry for developing new acid-suppression therapies.
• Generic Drug Manufacturing: Key raw material for the production of cost-effective generic versions of established PPI medications.
• Preclinical & Clinical Studies: Used in the formulation of dosage forms for pharmacological and toxicological evaluation.
• Process Chemistry Optimization: Employed in scaling up and optimizing synthetic routes for efficient commercial-scale API production.

Basic Information

Product Name	Leminoprazole
CAS No.	104340-86-5
Molecular Formula	C16H14F3N3O2S
Molecular Weight	369.36 g/mol
Synonyms	Leminoprazole; (RS)-2-[[(4-Methoxy-3-methylpyridin-2-yl)methyl]sulfinyl]-5-(trifluoromethyl)-1H-benzimidazole; AGN 201904; AGN-201904; Leminoprazolum; UNII-6C6K2WQ8Q5
EINECS	Contact for details

Quality Control

Our Leminoprazole is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We adhere to ICH guidelines and relevant pharmacopeial standards for pharmaceutical intermediates. Every lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles, available upon request to support your regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.5%
Related Substances (HPLC)	Total impurities ≤ 1.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.