Description

Proglumide, Sodium Salt is a water-soluble salt form of the cholecystokinin (CCK) receptor antagonist, proglumide. This compound is valued for its enhanced solubility and bioavailability in research and development applications, particularly in neuroscience and gastroenterology. It is primarily utilized by pharmaceutical researchers, academic institutions, and R&D laboratories investigating CCK-mediated pathways, gastric acid secretion, and potential therapeutic applications for pain and anxiety disorders.

Application

• Pharmacological Research: As a selective cholecystokinin (CCK) receptor antagonist for in vitro and in vivo studies.
• Neuroscience Studies: Investigation of CCK's role in pain modulation, anxiety, panic disorders, and satiety.
• Gastrointestinal Research: Study of gastric acid secretion, pancreatic exocrine function, and gut motility.
• Drug Discovery & Development: A reference standard or intermediate in the development of new therapeutic agents targeting CCK receptors.
• Academic & Institutional R&D: For fundamental research into hormone receptor interactions and signal transduction pathways.
• Biochemical Assays: Used as a tool compound in receptor binding assays and functional cellular tests.

Basic Information

Product Name	Proglumide, Sodium Salt
CAS No.	99247-33-3
Molecular Formula	C18H25N3NaO4
Molecular Weight	370.40 g/mol
Synonyms	Proglumide Sodium; Sodium Proglumide; 4-Benzamido-N,N-dipropylglutaramic acid sodium salt; N-(Dipropylcarbamoyl)-4-benzamidoglutaramic acid sodium salt; Benzoyl-N,N-dipropyl-DL-isoglutamine sodium salt; CCK antagonist (proglumide sodium); CR 1409 (sodium salt); Lorglumide sodium (related analog)
EINECS	Contact for details

Quality Control

Our Proglumide, Sodium Salt is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification (IR, NMR), purity assay (HPLC), and control of related substances and residual solvents, to ensure it meets high-purity standards suitable for research applications. A Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Water Content (KF)	≤5.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.