Description

n-Methylstreptothricin F is a chemically modified derivative of the streptothricin class of antibiotics, characterized by the addition of a methyl group to the streptolidine moiety. This structural modification is of significant interest for research into the structure-activity relationships of natural product antibiotics and for the development of novel bioactive compounds. It serves as a critical reference standard and intermediate for pharmaceutical research, particularly in the study of antibacterial mechanisms and resistance. Key industries that utilize this compound include pharmaceutical R&D, academic research, and biotechnology sectors focused on antimicrobial discovery.

Application

• Pharmaceutical Reference Standard: Used as a high-purity analytical standard for quality control and method development in antibiotic research.
• Biochemical Research: Employed in studies investigating the mechanism of action and bacterial resistance pathways of streptothricin-class antibiotics.
• Medicinal Chemistry Intermediate: Serves as a key building block or precursor for the semi-synthesis of novel antibiotic analogs and derivatives.
• Microbiology Studies: Applied in in vitro assays to evaluate antimicrobial activity against various bacterial strains.
• Academic & Institutional Research: Utilized in university and laboratory settings for fundamental research in organic chemistry and natural product biosynthesis.

Basic Information

Product Name	n-Methylstreptothricin F
CAS No.	99237-10-2
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	N-Methylstreptothricin F; Methylstreptothricin F; Antibiotic LL-AB664; LL-AB664; Streptothricin F methyl derivative; N-Methyl-gulosylstreptothricin F; (S)-4-Amino-2-[[(2S,3R,4R,5S,6R)-4,5-diamino-6-[[(2S,3S,6S)-3-amino-6-methyl-2-oxoazepan-1-yl]methyl]-3-hydroxyoxan-2-yl]oxy]-N-methyl-4-oxobutanoic acid
EINECS	Contact for details

Quality Control

Our n-Methylstreptothricin F is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including chromatographic purity analysis and identity confirmation, to ensure it meets the high standards required for research applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and identification results is provided with every shipment to guarantee traceability and consistency for your critical work.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as specified on the label or COA. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.