Description

Bicyclo[2.2.2]Oct-5-Ene-2-Carbonyl Chloride, 2-Methyl- (6Ci) is a highly reactive and versatile bicyclic acid chloride derivative, serving as a critical building block in advanced organic synthesis. Its unique strained bicyclic structure and reactive carbonyl chloride group make it invaluable for introducing complex, rigid molecular frameworks. This compound is essential for research chemists and process development scientists in the pharmaceutical and agrochemical industries who require high-purity intermediates for constructing novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those requiring rigid, three-dimensional scaffolds to enhance binding affinity and metabolic stability.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where the bicyclic core contributes to unique biological activity.
• Material Science Research: Employed in the creation of specialty polymers and advanced organic materials with specific thermal or mechanical properties.
• Ligand and Catalyst Development: Serves as a starting point for synthesizing sophisticated chiral ligands and organocatalysts used in asymmetric synthesis.
• Academic & R&D Laboratories: A valuable reagent for methodological studies and exploring new chemical transformations involving strained olefins and acid chlorides.

Basic Information

Product Name	Bicyclo[2.2.2]Oct-5-Ene-2-Carbonyl Chloride, 2-Methyl- (6Ci)
CAS No.	99187-84-5
Molecular Formula	C10H11ClO
Molecular Weight	182.65 g/mol
Synonyms	2-Methylbicyclo[2.2.2]oct-5-ene-2-carbonyl chloride; 2-Methyl-2-bicyclo[2.2.2]oct-5-ene-1-carbonyl chloride; 2-Methylbicyclo[2.2.2]oct-5-ene-1-carbonyl chloride; 2-Methyl-5-norbornene-2-carbonyl chloride (ambiguous); Bicyclo[2.2.2]oct-5-ene-2-carbonyl chloride, 2-methyl-; 99187-84-5; 2-Methyl-2-bicyclo[2.2.2]oct-5-enecarbonyl chloride
EINECS	Contact for details

Quality Control

Every batch of Bicyclo[2.2.2]Oct-5-Ene-2-Carbonyl Chloride, 2-Methyl- undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our quality assurance protocols are designed to meet the stringent requirements of cGMP and ISO standards for advanced chemical intermediates. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay (Titration)	95.0 - 102.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.