Description

1,4-Benzodioxan-2-Carbonyl Chloride, 3-Methyl- (6Ci) is a specialized organic intermediate featuring a reactive acid chloride functional group. This compound is critical for introducing the 3-methyl-1,4-benzodioxane moiety into target molecules, enabling advanced synthesis in pharmaceutical and agrochemical research. It is primarily sought by R&D chemists and process development scientists for constructing complex heterocyclic frameworks, particularly in the development of active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, especially those targeting neurological and cardiovascular pathways.
• Agrochemical Research: Used in creating novel herbicides, fungicides, and insecticides that incorporate the benzodioxane structure for enhanced activity.
• Organic Synthesis Reagent: Serves as an acylating agent in peptide coupling and other condensation reactions to form amides or esters.
• Material Science Precursor: Potential monomer or cross-linking agent in the development of specialty polymers with specific thermal or optical properties.
• Chemical Biology Probes: Useful for labeling or modifying biomolecules to study biological processes and interactions.

Basic Information

Product Name	1,4-Benzodioxan-2-Carbonyl Chloride, 3-Methyl- (6Ci)
CAS No.	99184-03-9
Molecular Formula	C10H9ClO3
Molecular Weight	212.63 g/mol
Synonyms	3-Methyl-1,4-benzodioxane-2-carbonyl chloride; 3-Methyl-2,3-dihydro-1,4-benzodioxine-2-carbonyl chloride; 2,3-Dihydro-3-methyl-1,4-benzodioxin-2-carbonyl chloride; 3-Methyl-1,4-benzodioxan-2-carboxylic acid chloride; 3-Methyl-2,3-dihydrobenzo[b][1,4]dioxine-2-carbonyl chloride
EINECS	Contact for details

Quality Control

Our production of 1,4-Benzodioxan-2-Carbonyl Chloride, 3-Methyl- (6Ci) adheres to stringent internal quality standards to ensure batch-to-batch consistency and reliability for your critical syntheses. Each lot is analyzed using advanced chromatographic and spectroscopic techniques. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment. We support cGMP-compliant manufacturing for advanced pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong bases, oxidizing agents, and sources of ignition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.