Description

3-(1-Naphthyl)Propionyl Chloride is a specialized organic acid chloride derivative of 1-naphthylpropionic acid. This compound serves as a critical high-purity building block in advanced organic synthesis, enabling the efficient introduction of the 1-naphthylpropionyl moiety. It is primarily utilized by pharmaceutical R&D and fine chemical industries for the production of active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: Key reagent in the synthesis of novel drug candidates and active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders.
• Agrochemical Synthesis: Used as a precursor for developing advanced herbicides, fungicides, and plant growth regulators with enhanced efficacy.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Polymer Chemistry: Serves as a monomer or modifying agent for creating specialty polymers with unique thermal or optical properties.
• Material Science Research: Utilized in the development of organic semiconductors, liquid crystals, and other functional organic materials.
• Peptide and Protein Modification: Acts as an acylating agent for modifying amino acid side chains in peptide synthesis and bioconjugation.

Basic Information

Product Name	3-(1-Naphthyl)Propionyl Chloride
CAS No.	99124-56-8
Molecular Formula	C₁₃H₁₁ClO
Molecular Weight	218.68 g/mol
Synonyms	1-Naphthalenepropanoyl Chloride; 3-(1-Naphthyl)Propanoic Acid Chloride; 3-(Naphthalen-1-yl)Propanoyl Chloride; 1-Naphthylpropionyl Chloride; α-Naphthylpropionyl Chloride; 3-(1-Naphthyl)Propionyl Chloride; Naphthalene-1-propionyl chloride; 99124-56-8
EINECS	Contact for details

Quality Control

Our 3-(1-Naphthyl)Propionyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets exacting standards for sensitive synthetic applications. Comprehensive Certificates of Analysis (COA) documenting all critical parameters are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and reacts with strong acids/organic solvents; ensure the container is kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation. Keep away from heat, open flames, and incompatible materials such as bases, alcohols, and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.