Description

1-(4-Iodophenyl)-2-Methylpropan-1-One is a specialized aromatic ketone compound featuring an iodine substituent on the phenyl ring. This structure makes it a valuable intermediate in advanced organic synthesis, particularly for constructing complex molecules where the iodine atom serves as a versatile handle for further functionalization via cross-coupling reactions. It is primarily sought after by research institutions and pharmaceutical development companies engaged in the creation of novel active pharmaceutical ingredients (APIs), agrochemicals, and advanced materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, especially in medicinal chemistry research for creating libraries of novel compounds.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides, where its structure can be incorporated into bioactive molecules.
• Material Science: Serves as a precursor for synthesizing specialized monomers or ligands used in catalysts and advanced polymeric materials.
• Cross-Coupling Reactions: The iodine atom is pivotal in palladium-catalyzed reactions like Suzuki, Stille, and Heck couplings, enabling efficient carbon-carbon bond formation.
• Chemical Synthesis: Employed in academic and industrial R&D labs for exploring new synthetic pathways and methodologies in organic chemistry.

Basic Information

Product Name	1-(4-Iodophenyl)-2-Methylpropan-1-One
CAS No.	99059-63-9
Molecular Formula	C10H11IO
Molecular Weight	274.10 g/mol
Synonyms	4'-Iodoisobutyrophenone; 1-(4-Iodophenyl)-2-methyl-1-propanone; p-Iodoisobutyrophenone; 2-Methyl-1-(4-iodophenyl)propan-1-one; Isobutyrophenone, 4'-iodo-; 4-Iodoisobutyrophenone; α,α-Dimethyl-4-iodoacetophenone
EINECS	Contact for details

Quality Control

Our production of 1-(4-Iodophenyl)-2-Methylpropan-1-One adheres to stringent quality management protocols. Each batch is characterized and tested to ensure identity, purity, and consistency, meeting the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing specifications such as assay (by HPLC), identity (by IR/NMR), and impurity profile is provided with every shipment to guarantee traceability and reliability for your critical synthesis work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (typically 15-25°C). Keep away from heat, sparks, and open flames. Due to its light-sensitive nature, handling and storage should minimize exposure to direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residue on Ignition	< 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.