Description

1H-Pyrazole-4-Carbonyl Chloride, 3-Amino-1-(2-Butenyl)- (9Ci) is a specialized heterocyclic building block featuring both an amino group and a highly reactive acid chloride moiety. This compound is valued for its versatility as a key intermediate in the synthesis of more complex molecules, enabling the formation of amide and peptide bonds under mild conditions. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for constructing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, particularly in the development of kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging its pyrazole core for biological activity.
• Chemical Research & Development: Serves as a versatile reagent in academic and industrial R&D labs for exploring new heterocyclic chemistry and creating custom molecular libraries.
• Peptidomimetic Chemistry: The reactive carbonyl chloride group facilitates the efficient introduction of the pyrazole-amino acid motif into peptide chains, creating peptidomimetics.
• Material Science Precursor: Potential use in the synthesis of functionalized polymers or ligands for metal-organic frameworks (MOFs) and catalysts.

Basic Information

Product Name	1H-Pyrazole-4-Carbonyl Chloride, 3-Amino-1-(2-Butenyl)- (9Ci)
CAS No.	99007-18-8
Molecular Formula	C8H10ClN3O
Molecular Weight	199.64 g/mol
Synonyms	3-Amino-1-(2-butenyl)-1H-pyrazole-4-carbonyl chloride; 1-(But-2-en-1-yl)-3-amino-1H-pyrazole-4-carbonyl chloride; 3-Amino-1-(but-2-en-1-yl)-1H-pyrazole-4-carbonyl chloride; 1H-Pyrazole-4-carbonyl chloride, 3-amino-1-(2-butenyl)-; 99007-18-8; 1-(2-Butenyl)-3-amino-1H-pyrazole-4-carbonyl chloride
EINECS	Contact for details

Quality Control

Our 1H-Pyrazole-4-Carbonyl Chloride, 3-Amino-1-(2-Butenyl)- is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable, and our quality systems are designed to meet the stringent requirements of pharmaceutical and advanced chemical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Solubility	Soluble in common organic solvents (DMF, DCM, THF)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.