Description

3-Furancarbonyl Chloride, Tetrahydro-2,2-Dimethyl-, (R)- (9Ci) is a high-value, chiral building block characterized by its reactive acid chloride functional group on a tetrahydrofuran scaffold. This compound matters for its role as a key intermediate in the synthesis of complex, optically active molecules, enabling precise stereochemical control in final products. It is primarily needed by research and development chemists and process scale-up teams in the pharmaceutical and agrochemical industries for creating novel active ingredients and fine chemicals.

Application

• As a chiral acylating agent in the synthesis of pharmaceutical intermediates, particularly for central nervous system (CNS) and antiviral drug candidates.
• Building block for the preparation of novel tetrahydrofuran-based ligands and catalysts used in asymmetric synthesis.
• Intermediate in the research and development of advanced agrochemicals, such as herbicides and fungicides with specific stereochemistry.
• Key starting material for the synthesis of complex natural product analogs and fragrances requiring the (R)-configured tetrahydrofuran moiety.
• Used in process chemistry and scale-up for the cGMP production of target molecules.
• Reagent in academic and industrial research for exploring new methodologies in organic and medicinal chemistry.

Basic Information

Product Name	3-Furancarbonyl Chloride, Tetrahydro-2,2-Dimethyl-, (R)- (9Ci)
CAS No.	98891-56-6
Molecular Formula	C7H11ClO2
Molecular Weight	162.61 g/mol
Synonyms	(R)-2,2-Dimethyltetrahydrofuran-3-carbonyl chloride; (3R)-2,2-Dimethyltetrahydro-3-furoyl chloride; (R)-2,2-Dimethyl-dihydro-3-furoyl chloride; (R)-2,2-Dimethyl-3-tetrahydrofurancarbonyl chloride; (R)-2,2-Dimethyl-3-furoyl chloride (ambiguous); Tetrahydro-2,2-dimethyl-3-furancarbonyl chloride, (R)-; 98891-56-6; (R)-DTFC-Cl
EINECS	Contact for details

Quality Control

Our 3-Furancarbonyl Chloride, Tetrahydro-2,2-Dimethyl-, (R)- (9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and enantiomeric excess are available upon request to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic and moisture-sensitive nature, store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place. Recommended storage temperature is 2-8°C for long-term stability. Keep away from strong bases and moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.