Description

Bicyclo[4.1.0]Hept-2-Ene-7-Carbonyl Chloride, 3,6-Dimethyl-, [1S-(1Alpha,6Alpha,7Alpha)]- (9Ci) is a high-value, stereochemically defined bicyclic building block and an advanced pharmaceutical intermediate. Its rigid, strained bicyclic structure and reactive acid chloride functional group make it a critical precursor for synthesizing complex molecules with specific three-dimensional architectures. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for creating novel active ingredients and chiral ligands.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel active pharmaceutical ingredients (APIs), especially in medicinal chemistry programs targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Synthesis: Used in the research and development of advanced crop protection agents and pesticides, where its unique bicyclic core can impart specific biological activity and stability.
• Chiral Ligand & Catalyst Development: Serves as a sophisticated precursor for constructing complex chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the development of specialty polymers and advanced organic materials that require rigid, functionalized monomer units.
• Academic & R&D Laboratories: A valuable tool for methodological studies in organic synthesis, particularly in cyclopropanation and ring-strain chemistry.

Basic Information

Product Name	Bicyclo[4.1.0]Hept-2-Ene-7-Carbonyl Chloride, 3,6-Dimethyl-, [1S-(1Alpha,6Alpha,7Alpha)]- (9Ci)
CAS No.	98875-03-7
Molecular Formula	C10H13ClO
Molecular Weight	184.66 g/mol
Synonyms	(1S,6R,7R)-3,6-Dimethylbicyclo[4.1.0]hept-2-ene-7-carbonyl chloride; (1S,6R,7R)-3,6-Dimethyl-7-bicyclo[4.1.0]hept-2-enecarbonyl chloride; 3,6-Dimethylbicyclo[4.1.0]hept-2-ene-7-carbonyl chloride, (1S,6R,7R)-; [1S-(1α,6α,7α)]-3,6-Dimethylbicyclo[4.1.0]hept-2-ene-7-carbonyl chloride; (1S,6α,7α)-3,6-Dimethylbicyclo[4.1.0]hept-2-ene-7-carbonyl chloride
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Every batch undergoes comprehensive analytical characterization, including chiral purity verification by HPLC, to ensure consistent stereochemical integrity and chemical purity critical for your synthetic applications. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting identity, assay, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.