Description

2'-Fluoro-4'-Hydroxyacetophenone is a fluorinated aromatic ketone derivative that serves as a versatile and critical building block in advanced organic synthesis. Its unique structure, featuring both a fluorine atom and a phenolic hydroxyl group, makes it a valuable intermediate for creating complex molecules with tailored properties. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly in fluorinated active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Building block for developing advanced pesticides and herbicides where the fluorine moiety enhances biological activity and stability.
• Liquid Crystal Materials: Used in the research and production of fluorinated compounds for electronic display applications.
• Organic Light-Emitting Diodes (OLEDs): Intermediate for synthesizing fluorinated charge-transport or emissive materials.
• Chemical Research: A valuable reagent for academic and industrial R&D in fluorine chemistry and medicinal chemistry.
• Fine Chemical Production: Employed in the custom synthesis of specialty fluorinated aromatics for various high-value applications.

Basic Information

Product Name	2'-Fluoro-4'-Hydroxyacetophenone
CAS No.	98619-07-9
Molecular Formula	C8H7FO2
Molecular Weight	154.14 g/mol
Synonyms	1-(2-Fluoro-4-hydroxyphenyl)ethanone; 2-Fluoro-4-hydroxyacetophenone; 4'-Hydroxy-2'-fluoroacetophenone; 2-Fluoro-4-acetylphenol; 4-Acetyl-3-fluorophenol; 1-Acetyl-2-fluoro-4-hydroxybenzene; Ethanone, 1-(2-fluoro-4-hydroxyphenyl)-
EINECS	Contact for details

Quality Control

Our 2'-Fluoro-4'-Hydroxyacetophenone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We support cGMP standards for pharmaceutical applications and can accommodate custom purity requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This product is light-sensitive (store away from light) and easily oxidized (store under inert atmosphere). Keep away from heat, sparks, and open flame. For long-term storage, consider maintaining under an inert atmosphere such as nitrogen or argon to preserve stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	108°C - 112°C
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Related Substances (HPLC)	Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.