Description

5-Phenyl-1,3,4-Oxadiazole-2-Carbonyl Chloride is a high-purity, reactive chemical intermediate essential for advanced organic synthesis. Its core value lies in its role as a versatile acylating agent, enabling the efficient construction of complex heterocyclic amides and hydrazides critical to modern research and development. This compound is primarily needed by pharmaceutical, agrochemical, and specialty chemical manufacturers for developing active ingredients, functional materials, and novel chemical entities.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing novel drug candidates, particularly those containing the 1,3,4-oxadiazole pharmacophore with potential biological activity.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides where the oxadiazole ring contributes to efficacy and stability.
• Polymer & Material Science: Serves as a monomer or cross-linking agent for creating high-performance polymers, liquid crystals, and specialty coatings.
• Organic Synthesis Reagent: A crucial acyl chloride for introducing the 5-phenyl-1,3,4-oxadiazole-2-carbonyl moiety into target molecules under mild conditions.
• Peptide Mimetics & Bioconjugation: Facilitates the synthesis of peptide analogs and bioconjugates for biochemical and diagnostic applications.
• Research & Development: Employed in academic and industrial R&D labs for exploring new chemical reactions and developing novel heterocyclic compounds.

Basic Information

Product Name	5-Phenyl-1,3,4-Oxadiazole-2-Carbonyl Chloride
CAS No.	98591-60-7
Molecular Formula	C9H5ClN2O2
Molecular Weight	208.60 g/mol
Synonyms	2-(Chlorocarbonyl)-5-phenyl-1,3,4-oxadiazole; 5-Phenyl-1,3,4-oxadiazole-2-carbonyl chloride; 1,3,4-Oxadiazole-2-carbonyl chloride, 5-phenyl-; 2-Phenyl-5-(chloroformyl)-1,3,4-oxadiazole; Oxadiazole carbonyl chloride; 98591-60-7; 5-Phenyl-[1,3,4]oxadiazole-2-carbonyl chloride
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for high-purity chemical intermediates. Every batch is characterized using advanced analytical techniques including HPLC, NMR, and IR spectroscopy to confirm identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are available upon request, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases, alcohols, and amines.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.