Description

(22R)-1α,3β,22,27-Tetrahydroxyergosta-5,24-Diene-26-Oic Acid 26,22-Lactone is a high-purity, complex steroidal lactone compound of significant interest in advanced research and development. This specialized ergostane derivative serves as a critical reference standard and key intermediate for the synthesis of novel bioactive molecules. It is primarily sought by pharmaceutical R&D laboratories, biotechnology firms, and academic research institutions focused on exploring new therapeutic pathways.

Application

• Pharmaceutical Reference Standard: Used for the qualitative and quantitative analysis of related steroidal compounds in method development and quality control.
• Biochemical Research: Serves as a precursor or intermediate in the synthesis of novel steroid-based drug candidates and probes for biological studies.
• Natural Product Synthesis: A key building block for the semi-synthesis or total synthesis of complex natural products with potential bioactivity.
• Metabolic Pathway Studies: Utilized as a standard or inhibitor in research focused on sterol and steroid biosynthesis pathways.
• Analytical Chemistry: Employed as a high-purity calibrant in chromatographic (HPLC, LC-MS) and spectroscopic analyses.

Basic Information

Item	Details
Product Name	(22R)-1α,3β,22,27-Tetrahydroxyergosta-5,24-Diene-26-Oic Acid 26,22-Lactone
CAS No.	98569-64-3
Molecular Formula	C₂₈H₄₂O₆
Molecular Weight	474.64 g/mol
Synonyms	1α,3β,22R,27-Tetrahydroxyergosta-5,24-dien-26-oic acid 26,22-lactone; (22R)-Ergosta-5,24-diene-1α,3β,22,27-tetrol, 26-oic acid 26,22-lactone; 22R-Hydroxy Withanolide D analogue; 27-Hydroxy Withanolide D derivative; Steroidal Lactone 98569-64-3; Ergostane Tetrol Lactone; 1α,3β,22R,27-Tetrahydroxyergost-5,24-dien-26-oic acid δ-lactone
EINECS	Contact for details

Quality Control

Our (22R)-1α,3β,22,27-Tetrahydroxyergosta-5,24-Diene-26-Oic Acid 26,22-Lactone is produced and handled under strict quality management protocols. Each batch undergoes comprehensive analytical characterization, including HPLC for purity, NMR, and MS for structural confirmation, to ensure identity and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.